Avana is a brand name for the medication avanafil, which belongs to the class of phosphodiesterase type 5 (PDE5) inhibitors. Avanafil is primarily used to treat erectile dysfunction (ED) in men. Avanafil, like other PDE5 inhibitors such as sildenafil, tadalafil, and vardenafil, works by increasing blood flow to the penis. It achieves this by inhibiting the action of PDE5, an enzyme that breaks down cyclic guanosine monophosphate (cGMP). Elevated levels of cGMP lead to relaxation of smooth muscle cells in the blood vessels of the penis, allowing increased blood flow and facilitating an erection.

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